1453
| Years: 1450 1451 1452 - 1453 - 1454 1455 1456 | |
| Decades: 1420s 1430s 1440s - 1450s - 1460s 1470s 1480s | |
| Centuries: 14th century - 15th century - 16th century | |
- May 29 - Fall of Constantinople to Ottoman Sultan Mehmed II the Conqueror, marking the end of the Byzantine Empire (Eastern Roman Empire).
- July 17 - Battle of Castillon. The French under Jean Bureau utterly defeat the English under the Earl of Shrewsbury, who is killed
- October 19 - The French recapture of Bordeaux brings the Hundred Years War to a close, with the English retaining only Calais on French soil.
- October 13 - Edward of Westminster, Prince of Wales, only son of King Henry VI of England
- Alfonso d'Albuquerque, Portugese admiral
- May 29 - Constantine XI, last Byzantine Emperor